Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity associated with bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or research is essential for ensuring the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound from the synthesis of imatinib, a drug that targets particular kinds of most cancers, including Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their examine is very important for optimizing the output approach and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is made use of to treat breast cancer, and these b-D-Ribofuranose intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Utilized in the remedy of breast most cancers. Numerous intermediates help in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug efficient in treating cancers for example ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the procedure of colorectal cancer and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have different apps, together with antiviral Attributes.
Vildagliptin Intermediates: Utilized in the production of vildagliptin, an oral drug for form 2 N-Pyrazinylcarbonyl-L-phenylalanine diabetic issues that inhibits the enzyme DPP-4 to control blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of assorted gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication utilized to manage style two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).